Recent dermatology visit is associated with thinner Breslow depth nodular melanomas

Is physician detection associated with thinner melanomas?

CONTEXT In cutaneous melanoma, tumor depth remains the best biologic predictor of patient survival. Detection of prognostically favorable lesions may be associated with improved survival in patients with melanoma. OBJECTIVE To determine melanoma detection patterns and relate them to tumor thickness. DESIGN Interview survey. SETTING AND PATIENTS All patients with newly detected primary cut...

Tumor necrosis is associated with increased αvβ3 expression and poor prognosis in nodular cutaneous melanomas

Recent Advances in Dermatology

Vitamin D Deficiency at Melanoma Diagnosis Is Associated with Higher Breslow Thickness

BACKGROUND Epidemiological evidence shows that people with thicker, or higher stage, melanomas have lower vitamin D status compared to those with thinner tumours. Evidence from experimental studies is inconsistent, but some suggest that administration of vitamin D metabolites can decrease tumour aggressiveness. OBJECTIVES Determine the relationship between vitamin D status at diagnosis and me...

Cigarette smoking is associated with thinner cingulate and insular cortices in patients with severe mental illness.

BACKGROUND Magnetic resonance imaging (MRI) studies show reduced cortical thickness in patients with schizophrenia and bipolar disorder. These subtle brain abnormalities may provide insight into illness mechanisms. However, environmental and lifestyle-related factors, such as cigarette smoking, may contribute to brain structure changes. Cigarette smoking is highly prevalent in patients with sev...